Nucleic Acid Purification

The difference between Nucleic Acid Purification and Nucleic Acid Isolation

The terms Nucleic Acid Purification and Nucleic Acid Isolation are used interchangeably, but in fact are two different applications. Nucleic Acid Isolation is the process of extracting DNA and/or RNA from the cell. There are multiple methods that can be used for this process, and a few of these methods are described on the Nucleic Acid Isolation page.

Nucleic Acid Purification is the process to reduce or even eliminate the contamination from Nucleic Acid samples. There are two reasons to perform a Nucleic Acid Purification:

1. When the isolated DNA and/or RNA needs to be purer
2. When a specific molecular weight of DNA is necessary for downstream applications.

Nucleic Acid Purification is the process of specifically obtaining the desired molecule of interest, naturally the purity will be extremely high after this procedure.